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First Steps Towards a Risk of Bias Corpus of Randomized Controlled Trials
Type of publication: Article
Citation:
Publication status: Published
Journal: CARING IS SHARING--EXPLOITING THE VALUE IN DATA FOR HEALTH AND INNOVATION
Series: Studies in Health Technology and Informatics
Year: 2023
Month: May
Pages: 586
URL: https://ebooks.iospress.nl/doi...
DOI: 10.3233/SHTI230210
Abstract: Risk of bias (RoB) assessment of randomized clinical trials (RCTs) is vital to conducting systematic reviews. Manual RoB assessment for hundreds of RCTs is a cognitively demanding, lengthy process and is prone to subjective judgment. Supervised machine learning (ML) can help to accelerate this process but requires a hand-labelled corpus. There are currently no RoB annotation guidelines for randomized clinical trials or annotated corpora. In this pilot project, we test the practicality of directly using the revised Cochrane RoB 2.0 guidelines for developing an RoB annotated corpus using a novel multi-level annotation scheme. We report inter-annotator agreement among four annotators who used Cochrane RoB 2.0 guidelines. The agreement ranges between 0% for some bias classes and 76% for others. Finally, we discuss the shortcomings of this direct translation of annotation guidelines and scheme and suggest approaches to improve them to obtain an RoB annotated corpus suitable for ML.
Keywords: corpus, Information extraction, Natural Language Processing, risk of bias, systematic reviews
Authors Dhrangadhariya, Anjani
Hilfiker, Roger
Sattelmayer, Martin
Giacomino, Katia
Caliesch, Rahel
Simone, Elsig
Naderi, Nona
Müller, Henning
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Total mark: 0
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