TY - CONF ID - AA02022 T1 - Comparison of MR preprocessing strategies and sequences for radiomics-based MGMT prediction A1 - Abler, Daniel A1 - Andrearczyk, Vincent A1 - Oreiller, Valentin A1 - Barranco Garcia, Javier A1 - Vuong, Diem A1 - Tanadini-Lang, Stephanie A1 - Guckenberger, Matthias A1 - Reyes, Mauricio A1 - Depeursinge, Adrien ED - Crimi, Alessandro ED - Bakas, Spyridon TI - Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries (MICCAI/BrainLes 2021) T3 - LNCS Y1 - 2022 VL - 12963 SP - 367–380 PB - Springer International Publishing CY - Cham SN - 978-3-031-09002-8 M2 - doi: 10.1007/978-3-031-09002-8_33 N2 - Hypermethylation of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter in glioblastoma (GBM) is a predictive biomarker associated with improved treatment outcome. In clinical practice, MGMT methylation status is determined by biopsy or after surgical removal of the tumor. This study aims to investigate the feasibility of non-invasive medical imaging based “radio-genomic” surrogate markers of MGMT methylation status. ER -